Webinar 5/2026 เรื่อง The Power of HPLC/UHPLC Stationary Phase Selectivity วันพุธที่ 15 กรกฎาคม 2569 เวลา 14.00-16.00 น.

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Abstract

In this seminar, we review the parameters that affect the resolution in liquid chromatography. One of the most powerful parameters to vary is the stationary-phase selectivity. By varying the stationary phase chemistry, differing mechanisms of interaction with analyte molecules can be exploited to optimize the separation selectivity. With an understanding of the selectivity difference of phase chemistry, we introduce the complementary phase to cover a range of retention mechanisms,
namely hydrophobic, π-π interactions, dipole-dipole, hydrogen bonding, and shape selectivity, which can be utilized during method development to enhance separation selectivity and resolution.

Learning objective

• To empower the liquid chromatography method development strategy related to the stationary phase selectivity.
• To introduce the complementary stationary phase with a broad array of retention mechanisms.