TIPA-สมาคมเภสัชกรอุตสาหการ (ประเทศไทย)

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Webinar 11/2024 mRNA & pDNA manufacturing technologies – landscape, challenges, recommendations and case studies : October 30th, 2024,13.30-15.30 Hr

In this webinar, you will:

  • Get an overview of the RNA based therapeutics market
  • Learn plasmid DNA and mRNA manufacturing challenges and recommendations on purification process development
  • Learn end to end plasmid and mRNA manufacturing process workflows commonly used in pharmaceutical industry

Detailed description:

The upcoming webinar will focus on both plasmid DNA (pDNA) and mRNA manufacturing for clinical and commercial batches. It will begin with an overview of the RNA therapeutics market, followed by a detailed look at pDNA manufacturing, an essential raw material for mRNA and viral vector therapies. A generic manufacturing template will be presented to address key challenges such as high viscosity, shear sensitivity, and process impurities, along with relevant case studies. The session will then shift to the use of pDNA in mRNA production, highlighting the unique challenges of mRNA manufacturing, including the sensitivity of intermediates to temperature, mechanical stress, and nucleases. Recommendations for overcoming these challenges across in vitro transcription, purification, and formulation will also be discussed.

 

Agenda:

 

Time (TH)

Topic

Speaker

12.30 – 13.30

Call-in / Dry run / Audio checking

All

13.30 – 13.35

Greeting

Moderator

13.35 – 13.50

(15 mins)

1. Applications of RNA based technology in pharmaceuticals and mRNA pipeline distribution on disease and therapeutic area

Meghan Peng

13.50 – 13.55

(5 mins)

Q&A

Meghan Peng & Phunlap assist

13.55 – 14.35

(40 mins)

2.pDNA manufacturing template, challenge, and solutions

Phunlap Sirisuk

14.35 – 14.40

(5 mins)

Q&A

Phunlap Sirisuk

14.40 – 15.20

(40 mins)

3.mRNA manufacturing template, challenge, and solutions

·        mRNA template

·        Process and Formulation Material Selection for Efficient Bioprocessing

Megan Peng &

Rimson Muara Jaya

15.20 – 15.25

(5 mins)

Q&A

Meghan, Rimson and Phunlap assist

15.25 – 15.30

Feedback form, Closing

Moderator

 Recommend for: Researcher, R&D, PD and people who are working on pDNA, mRNA and Viral Vector

รหัสกิจกรรม2004-2-000-025-10-2567
  •  เภสัชกรที่เข้าฟังสัมมนาและผ่านการทดสอบ จะได้รับ 2 หน่วยกิตการศึกษาต่อเนื่อง